Fig. 5: Identification and validation of TLS induction following chemotherapy.
From: Synergistic induction of tertiary lymphoid structures by chemoimmunotherapy in bladder cancer

a Relative levels of IHC staining intensities in pre-NAC (n = 92) and post-NAC (n = 60) samples. Red labels indicate a significant decrease, blue labels indicate a significant decrease, and black labels indicate no significant changes. b Relative levels of IHC staining intensities in 54 paired pre-NAC and post-NAC samples. Red labels indicate a significant decrease, blue labels indicate a significant decrease, and black labels indicate no significant changes. c Representative IHC images of paired pre-NAC and post-NAC samples. d Comparison of TLS number relative to tumor area between pre-NAC and post-NAC samples. e Comparison of TLS size relative to tumor area between pre-NAC and post-NAC samples.