Fig. 4: A panel of differentially expressed miRNAs serves as Non-Invasive prognostic biomarkers in NSCLC. | British Journal of Cancer

Fig. 4: A panel of differentially expressed miRNAs serves as Non-Invasive prognostic biomarkers in NSCLC.

From: Circulating miRNA panels as a novel non-invasive diagnostic, prognostic, and potential predictive biomarkers in non-small cell lung cancer (NSCLC)

Fig. 4

a Kaplan–Meier plots of overall survival (OS) for the LUAD cohort showing significant prognostic miRNAs based on DE miRNA expression (n = 3, Log-rank test p < 0.05). The cut-off for high or low miRNA expression was assessed by the X-tile programme. b Multivariate Cox regressional hazard analysis for prognostic miRNAs (n = 3) in LUAD cohort with clinical variables such as stage, sex, and age (NS: non-significant, HRatio: hazard ratio). c Kaplan–Meier plots of OS for the LUSC cohort representing significant prognostic miRNAs according to DE miRNA expression (n = 7, Log-rank test p < 0.05). The cut-off for high or low miRNA expression was assessed by the X-tile programme. d Multivariate Cox regressional hazard analysis for prognostic miRNAs (n = 2) in the LUSC cohort with clinical variables such as stage, sex, and age (NS non-significant, HRatio hazard ratio).

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