Fig. 3: Associations of genetically-proxied inhibition of HMGCR, NPC1L1, and PCSK9 with colorectal cancer outcomes.

The estimates are the odds ratios associated with a 1-SD reduction in LDL-C, with error bars representing 95%CIs. Associations on the left panel were adjusted for the correlations between SNPs. OR Odds Ratio, CI confidence intervals, LDL-C low-density lipoprotein cholesterol, SD standard deviation.