Table 1 Univariate and multivariate Cox regression analysis of the EV p75NTR.

From: Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration

Variables

 

Univariate Cox

Multivariate Cox

  

HR

95% CI

p-value

HR

95%CI

p-value

Age

N = 165

1.00

0.98–1.02

0.747

-

-

-

Sex

Female/Male

N = 165

0.93

0.64–1.35

0.701

-

-

-

Stage

I/II/III/IV

N = 165

1.30

1.06–1.60

0.011

1.25

0.94–1.68

0.129

Grading

G1/G2/G3

N = 149

1.28

0.89–1.84

0.183

-

-

-

Resections

R0/R1

N = 123

1.20

0.66–2.18

0.546

-

-

-

Neoadjuvant chemotherapy

No/Yes

N = 162

1.92

1.17–3.13

0.009

2.15

1.18–3.91

0.012

Lymphatic invasion, L

No/Yes

N = 123

1.89

1.19–2.99

0.007

1.40

0.83–2.35

0.21

Venous invasion, V

No/Yes

N = 123

1.17

0.74–1.87

0.506

-

-

-

Neural invasion, Pn

No/Yes

N = 165

1.59

0.92–2.75

0.096

-

-

-

p75NTR

N = 165

1.15

1.06–1.24

0.0004

1.14

1.04–1.24

0.004