Table 1 Clinicopathologic characteristics of colorectal cancer patients stratified by mucinous differentiation.
Mucinous differentiation | |||||
|---|---|---|---|---|---|
Characteristic | Total N | 0% | 1–50% | >50% | P |
All cases | 1049 (100%) | 668 (64%) | 296 (28%) | 84 (8%) | |
Sex | 0.032 | ||||
Female | 518 (49%) | 310 (46%) | 164 (55%) | 44 (52%) | |
Male | 531 (51%) | 358 (54%) | 132 (45%) | 41 (48%) | |
Age (years) | 0.055 | ||||
<65 | 284 (27%) | 198 (30%) | 61 (21%) | 25 (29%) | |
65–75 | 369 (35%) | 230 (34%) | 109 (37%) | 30 (35%) | |
>75 | 396 (38%) | 240 (36%) | 126 (43%) | 30 (35%) | |
Year of operation | 0.497 | ||||
2000–2005 | 325 (31%) | 215 (32%) | 83 (28%) | 27 (32%) | |
2006–2010 | 334 (32%) | 213 (32%) | 99 (33%) | 22 (26%) | |
2011–2015 | 390 (37%) | 240 (36%) | 114 (39%) | 36 (42%) | |
Tumour location | <0.0001 | ||||
Proximal colon | 508 (48%) | 265 (40%) | 188 (64%) | 55 (65%) | |
Distal colon | 386 (37%) | 292 (44%) | 72 (24%) | 22 (26%) | |
Rectum | 155 (15%) | 111 (17%) | 36 (12%) | 8 (9%) | |
AJCC stage | 0.327 | ||||
I | 177 (17%) | 123 (18%) | 44 (15%) | 10 (12%) | |
II | 393 (37%) | 249 (37%) | 108 (37%) | 36 (42%) | |
III | 343 (33%) | 219 (33%) | 99 (33%) | 25 (29%) | |
IV | 136 (13%) | 77 (12%) | 45 (15%) | 14 (17%) | |
Tumour grade | 0.001 | ||||
Low-grade | 868 (83%) | 573 (86%) | 233 (79%) | 62 (73%) | |
High -grade | 181 (17%) | 95 (14%) | 63 (21%) | 23 (27%) | |
Lymphovascular invasion | 0.080 | ||||
No | 828 (79%) | 519 (78%) | 234 (79%) | 75 (88%) | |
Yes | 221 (21%) | 149 (22%) | 62 (21%) | 10 (12%) | |
MMR status | <0.0001 | ||||
MMR-proficient | 889 (85%) | 619 (93%) | 211 (71%) | 59 (69%) | |
MMR-deficient | 160 (15%) | 49 (7%) | 85 (29%) | 26 (31%) | |
BRAF statusa | <0.0001 | ||||
Wild-type | 880 (84%) | 617 (93%) | 206 (70%) | 57 (67%) | |
Mutant | 168 (16%) | 50 (8%) | 90 (30%) | 28 (33%) | |
