Fig. 1: B7-H3 is highly expressed in CRC.

a Representative images from IHC staining of B7-H3 in tumor and paratumor tissue of CRC. Brown color shows positive staining. Scale bar=100 µm. b Expression level of B7-H3 analyzed by IRS score between tumor and paratumor tissue. c Expression of B7-H3 in different TNM stages of CRC. d, e Relationship between B7-H3 expression and disease-free survival (d) or overall survival (e) analyzed by Kaplan-Meier survival analysis and log-rank test. **p < 0.01; N.S., no significance.