Fig. 3: Performances of exosomal ALPPL2 and THBS2 as early detection biomarkers for PDAC. | British Journal of Cancer

Fig. 3: Performances of exosomal ALPPL2 and THBS2 as early detection biomarkers for PDAC.

From: Exosomal ALPPL2 and THBS2 as biomarkers for early detection and disease monitoring of pancreatic ductal adenocarcinoma

Fig. 3

Concentrations of ALPPL2+ (a), THBS2+ (b), and interferometric (IM) imaging (c) exosomes in serum samples are plotted for individual subjects by groups as listed in Table 1. Concentrations are the average of three tetraspanin captures. ROC analysis was conducted to compare the performances of exosomal ALPPL2 (d) and THBS2 (e) in discriminating all stages of PDAC from healthy control (HC) and non-cancerous conditions (NCC), early stage (Stage I and II) PDAC from HC and NCC, NCC from HC, and early stage PDAC from NCC. ****P < 0.0001. ns not significant (P ≥ 0.05).

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