Fig. 6: Combinatorial effects of dual-RRV prodrug activator gene therapy in vitro. | Cancer Gene Therapy

Fig. 6: Combinatorial effects of dual-RRV prodrug activator gene therapy in vitro.

From: Dual-vector prodrug activator gene therapy using retroviral replicating vectors

Fig. 6

 Combination index values based on the cell viabilities in the experiments shown in Fig. 5 were calculated at different fraction-affected points with CalcuSyn software. The combination groups for infection were CD and CD (a), TK and TK (b), and CD and TK (c, d). Ca + Cg: AMLV-CD + GALV-CD; Ta + Tg: AMLV-TK + GALV-TK; Ca + Tg: AMLV-CD + GALV-TK; Cg + Ta: GALV-CD + AMLV-TK

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