Fig. 5 | Cancer Gene Therapy

Fig. 5

From: Oncolytic activity of HF10 in head and neck squamous cell carcinomas

Fig. 5

HF10 injection induced tumor necrosis, CD8+ T cell accumulation in and around the tumor, and antitumor and immune-stimulatory cytokine production. a After HF10 injection into SCC-VII tumors, we performed H&E, anti-HSV, and anti-CD8 staining. Scale bars, 100 μm. b The SCC-VII tumors were removed at 3 and 24 h after the second injections of HF10 or PBS. We analyzed IL-2, IFN-γ, and TNF-α in the tumors (*p < 0.05)

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