Fig. 6
From: Oncolytic activity of HF10 in head and neck squamous cell carcinomas
HF10 treatment-induced CD8+ T cell and granulocyte accumulation in the spleen and the production of antitumor and immune-stimulatory cytokines. a CD45+ leukocytes in the spleen were analyzed by flow cytometry for CD3+CD8+ T cells and Gr-1+CD11b− granulocytes in the spleen. b, c The splenocytes were co-cultured with the SCC-VII cells for 24 and 72 h. We analyzed the release of IFN-α, IFN-β, IFN-γ, TNF-α, IL-2, and IL-12 in the supernatants after 24 h (*p < 0.05) and IFN-γ and TNF-α after 72 h (*p < 0.05)
