Fig. 2: MyoD1-binding DNA fragments detected by ChIP-sequencing. | Cancer Gene Therapy

Fig. 2: MyoD1-binding DNA fragments detected by ChIP-sequencing.

From: MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells

Fig. 2

a, b The distribution of peaks in the Up2k, Down2k, intergenic, intron, and exon regions analyzed according to MyoD1 vs. IgG (M1) and MyoD1 vs. Input (M2). c The number of peaks in the Up2k region that exhibited >2-fold enrichment over M1 and M2 and in common. d The number of peaks in the Up2k region on different chromosomes in M1 and M2. e GO annotation of 57 genes possibly bound by MyoD1 in their Up2k regions in terms of biological process, cellular component, and molecular function. f P value and peak-related genes (PRGs) with pathway annotation displayed in six enriched KEGG pathways (p value < 0.05). cAMP signaling pathway (g) and glycosphingolipid biosynthesis—lacto and neolacto series pathway (h) and their PRGs. i The specific nonredundant consensus sequences with E value < 10 and position p value < 0.0001.

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