Fig. 5: Knockdown of FUT4 suppresses GC Cell migration and invasion. | Cancer Gene Therapy

Fig. 5: Knockdown of FUT4 suppresses GC Cell migration and invasion.

From: MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells

Fig. 5

a qRT-PCR analysis of FUT4 in BGC-823 cells transfected with NC-siRNA, FUT4 siRNA-1, and FUT4 siRNA-2. b The effects of knockdown of FUT4 on BGC-823 cell migration were determined by wound-healing assay at 0, 12, 24, 36, and 48 h. c The effects of knockdown of FUT4 on BGC-823 cell migration (up) and invasion (down) were determined by Transwell assay without (null) or with Matrigel. d Western blotting analysis of the levels of MMP-2, MMP-9, vimentin, and N-cadherin in knockdown of FUT4 on BGC-823 cells compared to the control. The significant differences were analyzed according to t-test (***p < 0.001).

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