Fig. 3: The Hippo pathway, YAP/TAZ, and AXL are enhanced in OS-D dCTCs. | Cancer Gene Therapy

Fig. 3: The Hippo pathway, YAP/TAZ, and AXL are enhanced in OS-D dCTCs.

From: Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma

Fig. 3

A Representative YAP-1, TAZ, and AXL immunofluorescence confocal microscopic staining and quantification, B within the total single cell, C the nuclear single cell, and D the averaged OS-D-2D, PT, and dCTC samples. 20 μm scale bars are shown. Scatter plots represent the mean value of three experiments for OS-D 2D-monolayer cultures and four experiments for the PT and dCTC. Bars represent standard deviations. PT primary tumor, dCTC derived circulating tumor cell.

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