Fig. 4: Synergistic effect of the MTOR inhibitor torin-1 and the AKT inhibitor capivasertib. | Cancer Gene Therapy

Fig. 4: Synergistic effect of the MTOR inhibitor torin-1 and the AKT inhibitor capivasertib.

From: Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia

Fig. 4

A Heatmap representation of Bliss interaction index for RCH-ACV cells treated with the MTOR inhibitor torin-1 and the AKT inhibitor capivasertib. Data represent the mean of three independent experiments. B Titration curve for RCH-ACV cells treated with torin-1 in combination with vehicle or capivasertib. Data represent mean ± SEM of three independent experiments. P values were calculated using non-linear regression analysis and curves were compared with the sum-of-squares F test. ns not significant, **p < 0.01.

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