Fig. 5: S100A9 suppresses the migration and invasion of PCa cells, and overexpression of S100A9 rescues this effect after knockdown of circ_0006156. | Cancer Gene Therapy

Fig. 5: S100A9 suppresses the migration and invasion of PCa cells, and overexpression of S100A9 rescues this effect after knockdown of circ_0006156.

From: CircRNA circ_0006156 inhibits the metastasis of prostate cancer by blocking the ubiquitination of S100A9

Fig. 5

AD qRT–PCR and western blot analyses of the inhibition and overexpression efficiency of S100A9 in PCa cells. E, F Transwell assays showed that S100A9 suppressed the migration and invasion of PCa cells. G, H Wound-healing assays showed that S100A9 weakened the migration of PCa cells. I, J Transwell and wound-healing assays showed that the migration and invasion abilities enhanced by knocking down circ_0006156 were partially inhibited by overexpressing S100A9.

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