Table 1 Relationship between CDK5RAP3 expression and baseline characteristics of patients.

From: CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages

Variables

Total

CDK5RAP3 expression

Low

High

χ2

P

Gender

   

0.397

0.529

 Male

180

93

87

  

 Female

61

28

33

  

Age at surgery (years)

   

0.359

0.549

 >65

100

53

47

  

 ≤65

141

68

73

  

BMI

   

0.451

0.502

 ≤25

202

22

17

  

 >25

39

99

103

  

Tumour size (mm)

   

1.198

0.274

 >45

122

66

56

  

 ≤45

119

55

64

  

Location of primary tumour

   

3.869

0.276

 Lower 1/3

113

59

54

  

 Middle 1/3

39

18

21

  

 Upper 1/3

57

24

33

  

 More than 1/3

32

20

12

  

Chemotherapy

   

1.589

0.207

 No

97

54

43

  

 Yes

144

67

77

  

Degree of differentiation

   

8.854

0.003

 Well/moderate

74

26

48

  

 Poor and not

167

95

72

  

Depth of invasion

   

0.748

0.862

 T1

31

15

16

  

 T2

23

11

12

  

 T3

99

53

46

  

 T4

88

42

46

  

Lymph node metastasis

   

4.1450

0.246

 N0

63

32

31

  

 N1

41

15

26

  

 N2

51

26

25

  

 N3

86

48

38

  

TNM stage

   

2.297

0.317

 I

39

21

18

  

 II

62

26

36

  

 III

140

74

66

  
  1. P < 0.05 marked in bold font shows statistical significance.
  2. An IHC scores of 4 points were used to stratify tumours with low versus high CDK5RAP3 expression.
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