Fig. 2: Silencing of TRAIP suppresses tumor cells proliferation and induces G1/S arrest though RB-E2F signaling. | Cancer Gene Therapy

Fig. 2: Silencing of TRAIP suppresses tumor cells proliferation and induces G1/S arrest though RB-E2F signaling.

From: Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT

Fig. 2

A Cell proliferation was examined 1, 2, 3, 4, and 5 days via CCK-8 assay. B Colony formation of TRAIP knockdown and overexpression group cells were photographed and colony numbers were illustrated in histogram. C Flow cytometry revealed the distribution of cell phase in the TNBC cell lines. D The expression of RB, phospho-RB, E2F1, Cyclin D1, CyclinE1 and P21 was examined by Western blot. All data are shown as the means ± SD of three experiments. (**P < 0.01, *P < 0.05).

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