Fig. 4: miR-590-3p directly targets TRAIP and represses TRAIP expression. | Cancer Gene Therapy

Fig. 4: miR-590-3p directly targets TRAIP and represses TRAIP expression.

From: Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT

Fig. 4

A The binding sites of miR590-3p and TRAIP 3′-UTR. B Luciferase analysis showed the inhibitory effect of miR-590-3p on expression of the luciferase reporter gene by binding TRAIP 3′-UTR. C Western blot showed the TRAIP protein was highly up-regulated in miR-590-3p inhibitor and down-regulated by miR-590-3p mimic. All data are shown as the means ± SD of three experiments. (**P < 0.01).

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