Fig. 2: PDPN is highly expressed in IDH-WT GBMs at mRNA and protein levels.
From: PDPN contributes to constructing immunosuppressive microenvironment in IDH wildtype glioma
A The expression profile of PDPN in 31 kinds of cancers and their paired normal tissues from TCGA database. B–D The relationship between PDPN mRNA expression and WHO glioma grades and IDH mutation status of glioma samples in the TCGA and CGGA databases. E–G The expression of PDPN in IDH-Mut-co-del LGG, IDH-Mut-non-co-del LGG, IDH-WT LGG, IDH-Mut GBM, and IDH-WT GBM. H, I PDPN showed lower expression both at mRNA and protein levels. J–L Higher PDPN level is observed with increasing tumor grade in glioma clinical samples (ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).
