Fig. 3: Effect of WWOX on the ability of MERIT40 to form nuclear foci.

A Hela cells were transfected with MERIT40 and WWOX expression vectors as indicated. After 48 h, cells were irradiated with 10 Gy and allowed to recover for 4 h before permeabilization, fixation, and immunostaining with anti-MERTI40 (red) and anti-WWOX (green) antibodies. The contours of the nuclei are indicated. B Histogram is the quantitation of the results (50 cells were counted in each condition, the experiment was done once).