Fig. 6: Breast tumors with altered expression(s) of MERIT40 and/or WWOX are associated with aneuploidy and poor prognosis. | Cancer Gene Therapy

Fig. 6: Breast tumors with altered expression(s) of MERIT40 and/or WWOX are associated with aneuploidy and poor prognosis.

From: WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

Fig. 6

A Levels of the aneuploidy score in tumors of the TCGA-breast cohort (n = 1025) presenting unaltered expressions of MERIT40 and WWOX (blue bar) versus altered expression(s) of MERIT40 and/or WWOX (red bar). B Kaplan–Meier curves showing the metastasis-free survival rates of patients with tumors presenting unaltered expressions of MERIT40 and WWOX (blue line) versus altered expression(s) of MERIT40 and/or WWOX (red line) in human breast tumors from the TCGA cohort (n = 1025).

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