Table 3 Multivariate COX analysis of MFS for MERIT40 expression levels in the series of 499 breast cancers.

From: WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

Characteristics

HRa

95% CIb

p valuec

MERIT40

≤2.205

1.0

 

0.03

 

>2.205

1.53

1.04–2.25

 

Macroscopic tumor size

≤25 mm

1.0

 

0.0037

 

>25 mm

1.59

1.16–2.17

 

Lymph node status

0

1.0

 

<0.0001

 

1–3 and >3

1.64

1.33–2.03

 

SBR histological grade

I

1.0

 

0.17 (NS)

 

II and III

1.19

0.93–1.51

 

PR status

Negative

1.0

 

0.27 (NS)

 

Positive

0.84

0.61–1.15

 
  1. aHazard ratio.
  2. b95% confidential interval.
  3. cMultivariate COX analysis.
  4. Significant values are shown in bold.