Fig. 1: The characterization and expression of hsa_circ_0013561 in OC. | Cancer Gene Therapy

Fig. 1: The characterization and expression of hsa_circ_0013561 in OC.

From: Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer

Fig. 1

A Schematic diagram illustrating the formation of hsa_circ_0013561. Hsa_circ_0013561 was back-spliced from an exon of SLC16A1, and its back-splicing junction was confirmed by Sanger sequencing. B FISH detection showed the expression and subcellular localization of hsa_circ_0013561 in normal, primary, and metastatic OC tissues. C The expression level of hsa_circ_0013561 in tumor tissues and normal controls, measured by FISH, **P < 0.01 vs. Normal. D The expression level of hsa_circ_0013561 in primary and metastatic OC tissues, measured by FISH, ***P < 0.001 vs. metastasis. E RT-qPCR assay showed the expression of hsa_circ_0013561 in normal ovarian cell (IOSE80) and different OC cells (SKOV3, OVCAR-3, ES-2, and A2780). *P < 0.05, **P < 0.01, ***P < 0.001 OC cells vs. IOSE80.

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