Fig. 3: Lineage characterization of cells comprising colon organoids treated with rapamycin.
From: Rapamycin rescues APC-mutated colon organoid differentiation
Representative images of immunohistochemical staining of the intestinal epithelial markers CDX2, Keratin20 (CK20), Muc2, the proliferation marker Ki67, and the mesenchymal marker VIM, for FAP1 and FAP2 colon organoids at day 45 following rapamycin treatment (R). Non-treated cells served as a negative control, and normal colon tissue served as a positive control. Arrows point for Muc2 staining. Scale bars 200 µM. VIM vimentin, R Rapamycin.
