Fig. 1: Macrophages infected with Mtb are primed for necroptosis | Cell Death & Differentiation

Fig. 1: Macrophages infected with Mtb are primed for necroptosis

From: Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

Fig. 1

a Western blot analysis of necroptosis-associated proteins in wild-type BMDMs infected with Mtb for 24 h or 48 h. Representative of four independent experiments. b Western blot analysis of MLKL levels in alveolar macrophages isolated from the BAL of both uninfected and Mtb-infected wild-type mice (three–four weeks post-infection). Lysates from three uninfected and three infected mice were pooled. Representative of two experiments. Protein levels relative to uninfected samples at each time point (and adjusted for actin loading) were quantitated by densitometry for certain panels, and appear below the panel to which they relate. Numbers to the right of the panels represent the positions of protein size markers (in kDa)

Back to article page