Table 1 Potential Sp1-interacting motifs in the 5′-upstream flanking region of the ACSL4 gene

From: Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Location (relative to TSS)

Sequence (5′ to 3′)

Orientation

GL1 (from − 286 to − 277)

GGGGTGGAGT

F

GL2 (from − 38 to − 29)

GGGGCGGGCG

F

GL3 (from − 23 to − 13)

GTGGGCCGAGC

R

  1. Table 1 Three potential Sp1-interacting motifs were identified within the region 500 bp upstream of the ACSL4 promoter based on the consensus GC-box sequence. The orientation (R; reverse, F; forward) and the location of each motif relative to the TSS are shown
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