Fig. 5
From: TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin
TXNDC12 interacts with β-catenin via the thioredoxin-like domain. a Immunoprecipitation of β-catenin with E-cadherin in the indicated HCC cells, as detected by immunoblot analysis. b E-cadherin and β-catenin expression in the indicated cells, as detected by an immunofluorescence assay. The merged images show overlays of E-cadherin (green) and β-catenin (red). The nuclei were stained by DAPI (blue). c Total cell lysates from five HCC cell lines were immunoprecipitated with an anti-TXNDC12 antibody or control IgG. The β-catenin and TXNDC12 levels are indicated. d 293T cells transfected with Flag-tagged full-length TXNDC12 or TXNDC12 fragments were immunoprecipitated with an anti-Flag antibody. The β-catenin and Flag-TXNDC12 (full-length or fragments) levels are indicated
