Fig. 5: Tumour intrinsic PD-L1 promotes Gas6 transcription and secretion. | Cell Death & Differentiation

Fig. 5: Tumour intrinsic PD-L1 promotes Gas6 transcription and secretion.

From: KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway

Fig. 5

a, b qRT-PCR analysis of Gas6 and PROS1 mRNA expression levels in stable PD-L1 knockdown and overexpression cell lines. c The basal secretion level of Gas6 in PD-L1 stable cell lines and control cells. Data were presented as the mean ± SD. Data were analysed using non-paired Student’s t test, one-way ANOVA analysis followed by Bonferroni’s post hoc test. **P < 0.01; ***P < 0.001 vs. control or as indicated.

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