Fig. 1: The high expression of CRSP8 in thyroid cancer cells and tissues, especially in ATC.
From: CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation
A The protein levels of CRSP8 in human normal thyroid cells, DTC cells, and ATC cells were detected by western blot. B The immunofluorescence analysis of the expression and localization of CRSP8 in human normal thyroid cells, DTC cells, and ATC cells. Scale bars, 25 μm. C CRSP8 expression in normal thyroid tissues, DTC tissues, and PDTC tissues was observed by immunohistochemistry staining. Scale bars, 200, 100 μm. D Relative expression of CRSP8 by tissue type was shown in the scatter plot. 12 normal, 12 DTC, and 5 PDTC/ATC tissue samples were analyzed. E Expression of CRSP8 in thyroid cancer based on individual cancer stages from UALCAN analysis. The data represent the mean ± SD of three independent experiments, and the level of significance was indicated by ***P < 0.001, **P < 0.01, *P < 0.05. ATC anaplastic thyroid cancer, DTC differentiated thyroid cancer, PDTC poorly differentiated thyroid cancer.
