Fig. 1: One IV injection of MSC-CS, but not MSC-UCS, transiently restores memory in 12-month-old APP/PS1 mice. | Cell Death & Differentiation

Fig. 1: One IV injection of MSC-CS, but not MSC-UCS, transiently restores memory in 12-month-old APP/PS1 mice.

From: Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice

Fig. 1

a Experimental design. b Comparison of the discrimination index (DI) of APP/PS1 mice and their age-matched WT littermates receiving either PBS, MSC-CS or MSC-UCS and tested in the NORT. DI of WT and APP/PS1 mice treated with PBS or MSC-CS and tested in the NORT 7 days (c) and 14 days (d) post-injection. Data are expressed as scatter plots with mean ± SEM. One-way ANOVA in b and d. Two-way ANOVA in c, *P < 0.05; **P < 0.01 Tukey’s multiple comparison post-hoc test.

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