Fig. 3: Single IV injection of MSC-CS improves the inflammatory phenotype of astrocytes.
From: Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice
a Confocal images of hippocampal slices from MSC-CS-treated and PBS-treated mice immunostained for GFAP. b GFAP-marked area quantification evidencing the degree of astrogliosis between treatment groups. c Hippocampal slices immunostained for TNFα and relative quantification in d. e Merge of hippocampal immunostaining for TNFα-GFAP-IBA1. f Hippocampal immunostaining for IL1β quantified in g; h Merge of hippocampal immunostaining for IL1β-GFAP-IBA1. Quantification data are expressed as scatter plots with mean ± SEM. *P < 0.05, Student’s t test.
