Fig. 7: Repeated delivery of MSC-CS appears to reduce AβO load around plaques in APP/PS1 mice.
From: Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice

Images of APP/PS1 mouse brain slices immunostained with the anti-AβOs A11 antibody showing the presence of AβOs in PBS- (a) and MSC-CS-treated (8 IN) 25-month-old mice (b); upper panels. Middle and lower panels depict a higher magnification of plaques in the cortex and the hippocampus of APP/PS1 mice showing AβO distribution (darker dots).