Table. 1 Criteria for the semi-quantitative evaluation of γH2AX staining by immunohistochemistry on mouse mammary tumors.

From: The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer

Negative

Weak punctate staining encompassing <50% of the nucleus of <50% of neoplastic cells

Weak positive

Moderate to strong punctate staining encompassing <50% of the nucleus of 50–75% of the neoplastic cells

Strong positive

Moderate to strong punctate staining encompassing up to 90% of the nucleus of >75% of neoplastic cells

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