Fig. 1: PTGDS was upregulated in DLBCL and associated with tumor progression. | Cell Death & Differentiation

Fig. 1: PTGDS was upregulated in DLBCL and associated with tumor progression.

From: Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling

Fig. 1

A and B Immunohistochemical staining for PTGDS expression was higher in DLBCL tissue (n = 120) than that in RHL samples (n = 32). Bar = 40 μm. C Higher serum PTGDS levels were found in DLBCL patients (n = 53) than healthy controls (n = 17). D Western blotting showed high expression of PTGDS in DLBCL cells. E Analysis of the association between clinical characteristics and PTGDS score in DLBCL. F and G Kaplan–Meier survival analysis of the association between PTGDS expression and PFS and OS in non-GCB and GCB patients, respectively. Data are shown as the mean ± SD. **p < 0.01; ***p < 0.001.

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