Fig. 1: Ctr-infection inhibits apoptosis independently of Mcl-1. | Cell Death & Differentiation

Fig. 1: Ctr-infection inhibits apoptosis independently of Mcl-1.

From: Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak

Fig. 1

A HeLa wt or Mcl-1-deficient cells were infected with Ctr (MOI = 5) for 24 h. Cells were treated with 1 µM staurosporine for 5 h. Apoptosis was measured by staining for cells expressing active caspase-3. Data show means/SEM of five independent experiments. ****p < 0.0001, two-way Anova for multiple comparisons. B Wt and Mcl-1-deficient HeLa cells were infected with Ctr (MOI = 5) for 24 h. Cells were treated with 10 µM ABT-737 for 12 h. Apoptosis was measured by staining for cells expressing active caspase-3. Data show means/SEM of three independent experiments. ****p < 0.0001, two way Anova for multiple comparisons.

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