Fig. 8: Expression of USP10 is positively correlated with ANLN level and poor prognosis of ESCC patients.
From: Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
A Representative images of USP10 immunohistochemical staining of ESCC and normal tissues (scale 200 and 50 μm). B Expression analysis of USP10 in 104 ESCC and normal tissue samples. C USP10 protein levels in 124 ESCC and normal tissues were analyzed based on the IPX0002501000 dataset from the iProX database. D, E The mRNA levels of USP10 in tumor and adjacent normal tissues of ESCC patients were analyzed based on the GeneChip data of GSE53625 from the GEO database (D). The mRNA levels of USP10 in ESCC tumors and adjacent normal tissues were analyzed based on the SRP064894 dataset in the SRA database (E). F–I The relation between USP10 and ANLN was determined using Pearson’s correlation analysis. J–L Kaplan–Meier curve analysis of the correlation between USP10 protein expression and overall survival in ESCC patients.
