Table 2 High and low serum TMAO groups’ comparison on general conditions, biochemical indicators and renal fibrosis related indicators.
Variables | Low TMAO group | High TMAO group | P value |
|---|---|---|---|
N = 15 | N = 15 | ||
Age | 34.87 ± 11.98 | 38.00 ± 12.93 | 0.49 |
Male (n,%) | 5 (33) | 8 (53) | 0.46 |
24 h urinary protein | 971 (440–1486) | 1440 (1026–1732) | 0.04* |
eGFR | 93.58 ± 27.80 | 81.86 ± 31.9 | 0.29 |
Serum Creatinine | 82.20 ± 27.42 | 98.80 ± 33.52 | 0.14 |
Blood Urine Nitrogen | 5.50 ± 2.12 | 6.77 ± 2.6 | 0.16 |
Serum Uric Acid | 349.5 ± 129.4 | 359 ± 93.9 | 0.82 |
Triglyceride | 1.647 ± 0.77 | 1.528 ± 0.55 | 0.63 |
Total cholesterol | 4.19 (3.82–5.01) | 4.50 (4.11–5.11) | 0.42 |
Complement C3 | 0.94 ± 0.17 | 0.86 ± 0.14 | 0.19 |
Complement C4 | 0.23 (0.18–0.27) | 0.26 ± 0.09 | 0.28 |
IgA | 2.59 ± 0.85 | 2.93 ± 0.75 | 0.26 |
IgG | 12.53 ± 2.93 | 11.28 ± 2.43 | 0.21 |
IgM | 1.35 ± 0.36 | 1.49 ± 0.41 | 0.36 |
Serum TMAO level | 87.97 ± 7.121 | 108.3 ± 6.321 | <0.01 |
Renal a-SMA | 4.88 ± 0.92 | 5.71 ± 1.24 | 0.04* |
Renal Col I | 3.42 ± 1.28 | 4.11 ± 1.67 | 0.02* |
Renal fibrotic area% | 24.15 ± 3.80 | 29.10 ± 6.07 | 0.01* |
