Fig. 3: BCL-XL modulates capillary-like structure formation
From: BCL-XL overexpression promotes tumor progression-associated properties
Quantification (tube length and number of intersection point) and representative images of capillary-like structure formation in (a) melanoma control (Mneo) and BCL-XL overexpressing (MXL90) cells, (b) MXL90 transfected with siRNA oligonucleotides against BCL-XL (si-BCL-XL) or scramble (si-Ctrl) target sequences, (c) MXL90 treated with 20 μM WEHI-539, (d) glioblastoma control (AN8) and BCL-XL overexpressing (AXL74) cells. Cells were plated on basement matrix extracts. Experiments have been performed under normoxic condition. Data were expressed as average ± standard deviation. *p < 0.05 after applying Student’s t-test
