Table 1 Claw pad model and metastasis LN number

From: RETRACTED ARTICLE: MicroRNA-221-3p, a TWIST2 target, promotes cervical cancer metastasis by directly targeting THBS2

Cell line

Experimental parameters

Metastases LN in vivo

 

Mouse strain

n

End-point (weeks)

No. total LNs

No. metastasis LNs

Metastatic ratio (%)

SiHa-luc-RFP-NC

BALB/c-nu

8

7–9

16

5

31.25

SiHa-luc-RFP-221-3p

BALB/c-nu

8

7–9

16

13

81.25a

HeLa-luc-RFP-NC

BALB/c-nu

8

7–9

16

4

25.00

HeLa-luc-RFP-221-3p

BALB/c-nu

8

7–9

16

11

68.75b

  1. aThe metastatic ratio has statistical significance between the SiHa-luc-RFP-221-3p group and SiHa-luc-RFP-NC group, (p = 0.011, χ2-test)
  2. bThe metastatic ratio has statistical significance between the HeLa-luc-RFP-221-3p group and HeLa-luc-RFP-NC group, (p = 0.032, χ2-test)
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