Fig. 2: miR-663 depletion induces apoptosis | Cell Death & Disease

Fig. 2: miR-663 depletion induces apoptosis

From: miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2

Fig. 2

The percentage of apoptotic NIH-H460 cells upon transfection with LNA-663 at 25 nM was analyzed by FACS and is shown as sub-G0 fraction. a one representative experiment, b mean of four independent experiments. Mean ± s.d. Annexin V staining showing apoptosis induction 72 h after LNA-663 transfection; c one representative experiment, d mean of two independent experiments. Mean ± s.d., e PARP-1 and CASPASE 3 cleavages at the indicated time points after LNA-663 transfection is shown by immunoblot.**p < 0.01, *p < 0.05

Back to article page