Fig. 1: PLK4 is elevated in NB tissues and PLK4 high expression is a poor prognostic factor | Cell Death & Disease

Fig. 1: PLK4 is elevated in NB tissues and PLK4 high expression is a poor prognostic factor

From: Polo-like kinase 4 mediates epithelial–mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway

Fig. 1

a Western blot analysis of PLK4 protein expression in NB tissues and paired normal tissues (T: tumor tissue, N: non-tumor tissue). b Real-time PCR analysis of PLK4 mRNA expression in NB tissues and relevant normal tissues. c Immunohistochemistry estimation of PLK4 and Ki-67 in NB tissues with different histological grades (scale bar, 1.0 mm). d Kaplan–Meier overall survival analysis of 85 NB patients with different PLK4 expression levels. e Kaplan–Meier progression-free survival analysis of 85 NB patients with different PLK4 expression levels. (***P < 0.001)

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