Fig. 4: PLK4 promoted epithelial–mesenchymal transition (EMT) in NB cells | Cell Death & Disease

Fig. 4: PLK4 promoted epithelial–mesenchymal transition (EMT) in NB cells

From: Polo-like kinase 4 mediates epithelial–mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway

Fig. 4

a Morphologic change in SK-N-BE(2) cells when PLK4 was downregulated. b Western blot of EMT-associated markers expression (epithelial marker E-cadherin, mesenchymal markers N-cadherin, vimentin, and Slug) in NB cell lines when PLK4 was downregulated. Immunofluorescence staining for EMT-associated markers (epithelial marker E-cadherin, mesenchymal markers vimentin, Slug) of sh-control and sh-PLK4 in SK-N-SH c and SK-N-BE(2) d cells, respectively. e Western blot of total Akt and phosphorylated Akt in sh-control and sh-PLK4 NB cells

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