Fig. 1: Rosmarinic acid (RA) attenuated cardiac dysfunction in mice following long-term pressure overload | Cell Death & Disease

Fig. 1: Rosmarinic acid (RA) attenuated cardiac dysfunction in mice following long-term pressure overload

From: Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling

Fig. 1

a The maximum carotid pressure of mice in the four groups (n = 13–14). b Fractional shortening (FS) of mice as determined via echocardiography at 8 weeks after the AB surgery (n = 15). c, d Hemodynamic analysis of mice with or without RA protection (n = 13–14). e, f Statistical results of the heart weight (HW)/body weight (BW) and HW/tibia length (TL) (n = 15). g, h Interventricular septal thickness at systole or diastole (IVSs or IVSd) (n = 15). i, j HE staining and statistical results of the cross sectional area (n = 6). k The relative mRNA level of Bnp normalized to Gapdh in mice (n = 6). Values represent the mean ± SEM. *P < 0.05 vs. the corresponding Sham group, #P < 0.05 vs. AB+Veh

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