Fig. 3: RAactivated AMPKα in vivo and knockout of AMPKα abrogated its protective effects | Cell Death & Disease

Fig. 3: RAactivated AMPKα in vivo and knockout of AMPKα abrogated its protective effects

From: Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling

Fig. 3

a-f Representative western blots and quantitative results in wild type (WT) mice (n = 6). g, h PSR staining and statistical results of average collagen volume in WT and AMPKα2 knockout (KO) hearts (n = 6). i FS in WT and KO mice (n = 8–10). Values represent the mean ± SEM. *P < 0.05 vs. the corresponding Sham group within WT mice, #P < 0.05 vs. AB+Veh in WT mice, &P < 0.05 vs. the corresponding Sham group in KO mice

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