Fig. 2: HBP1 is correlated with clinicopathological implications on patients with NPC | Cell Death & Disease

Fig. 2: HBP1 is correlated with clinicopathological implications on patients with NPC

From: HMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma

Fig. 2

a Heat map of 5 dys-regulated miRNAs were filtered from the GSE12452 data set. b MiR-29c is down-regulated in NPC biopsies (n = 31) compared with non-tumor NPE tissues (n = 10) in the GSE12452 dataset. MiR-29c expression levels were not associated with tumor-nodes-metastasis (TNM) stage (I, n = 6; II, n = 15, III, n = 15) and lymph node metastasis (LNM) (non-tumor, n = 10; NPC without LNM, n = 7; NPC with LNM, n = 24). c HBP1 is up-regulated in NPC biopsies (n = 31) compared with non-tumor NPE tissues (n = 10) in the GSE12452 dataset. HBP1 expression levels were not associated with TNM stage (I, n = 6; II, n = 15, III, n = 15) and LNM (non-tumor, n = 10; NPC without LNM, n = 7; NPC with LNM, n = 24). d Overall survival rates of 31 NPC patients were compared between the low HBP1 and high HBP1 expression groups, p = 0.0012. e Overall survival rates of 31 NPC patients were compared between the low miR-29c and high miR-29c expression groups, p = 0.0027

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