Fig. 7: Nrf2 antioxidant pathway inhibited the progression of EMT via suppressing the expression of Numb. | Cell Death & Disease

Fig. 7: Nrf2 antioxidant pathway inhibited the progression of EMT via suppressing the expression of Numb.

From: Nrf2 antioxidant pathway suppresses Numb-mediated epithelial–mesenchymal transition during pulmonary fibrosis

Fig. 7

Before SFN stimulation on RLE-6TN (a) and A549 (b), Numb siRNA was transfected in two cell lines. Finally we treated two cell lines with TGF-β1 stimulation. After densitometric analysis, β-actin was used as an internal reference for relative quantification. Data represent the mean ± SD (n = 3 per group), *P < 0.05, **P < 0.01 compared with vehicle group; +P < 0.05, ++P < 0.01 compared with TGF-β1 group; #P < 0.05, ##P < 0.01 compared with TGF-β1 + SFN group

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