Fig. 2: circRNA–miRNA network analysis. | Cell Death & Disease

Fig. 2: circRNA–miRNA network analysis.

From: Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk

Fig. 2

a The panorama network consists of 104 dysregulated circRNAs and their 343 target miRNAs. b Volcano plots are used for visualizing differential expression between two different conditions. The horizontal lines correspond to 2.0-fold (log2 scaled) up and down, respectively, and the vertical line represents an adjusted P value of 0.05 (−log10 scaled). The red and green points represent the upregulated- and downregulated-expressed miRNAs with statistical significance. c Hierarchical cluster analysis of the significantly upregulated and downregulated miRNAs. Each column represents a sample and each row represents a miRNA. Red strip represents high relative expression and green strip represents low relative expression. d Venn diagram demonstrating the intersection of differentially expressed miRNAs and predicted miRNA

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