Fig. 3: Knockdown of hepatic Gomafu improved insulin sensitivity in obese mice. | Cell Death & Disease

Fig. 3: Knockdown of hepatic Gomafu improved insulin sensitivity in obese mice.

From: Long noncoding RNA Gomafu upregulates Foxo1 expression to promote hepatic insulin resistance by sponging miR-139-5p

Fig. 3

The ob/ob mice were injected with si-control, siGomafu-1 or siGomafu-2 daily for 30 days via the tail vein. a Hepatic Gomafu expression was measured (n = 3 each group). b Random and fasting blood glucose levels were measured (n = 7 each group). c GTT was performed in mice fasted for 16 h (n = 7 each group) and the area under the curve (AUC) for blood glucose was calculated. d PTT was performed in mice fasted for 16 h (n = 7 each group). e ITT was performed in mice fasted for 4 h (n = 7 each group). *P < 0.05, **P < 0.01, compared to si-control group

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