Fig. 6: Cf influence on the cell death machinery association with lipid rafts.
From: Proteasome inhibition blocks necroptosis by attenuating death complex aggregation

a IB of RIPK1, RIPK3, pRIPK3, FADD, MLKL, TNFR1, and tUb in detergent-resistant membrane fractionations (DRM) of HT-29 cells 6 hpt under the indicated conditions. Caveolin-1 is a marker for DRM. b IB of RIPK1 immunoprecipitation (IB/IP) detecting tUb and RIPK1 in HT-29 cell lysates (4 hpt) under reducing conditions. c IB of 3xFLAG-tagged RIPK3 IP detecting tUb and FLAG in HT-29 cell lysates (4 hpt) under reducing conditions