Table 1 List of candidate inhibitory peptides and their protease targets
From: Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases
Peptide | Target |
|---|---|
z-FLF-cmk | Cathepsin G |
z-EPF-cmk | Cathepsin G |
z-GLF-cmk | Cathepsin G |
z-AFLF-cmk | Cathepsin G |
z-GLW-cmk | Cathepsin G |
z-GLK-cmk | Cathepsin G |
z-KAL-cmk | IL-36α cleavage site |
z-AAPV | Elastase |
z-API | Elastase |
z-APL | Elastase |
z-APV | Elastase |
z-ARPV | Elastase |
z-RPV | Elastase |
z-DTEF | IL-36β cleavage site |
z-PQR | IL-36β cleavage site |
z-RAV | IL-36γ cleavage site |
z-RPI | Elastase |
z-RPL | Elastase |
z-RPV | Elastase |
z-EPF-API-cmk | Cathepsin G/Elastase |
z-API-EPF-cmk | Elastase/Cathepsin G |
